Frank Salinas Ph.D., Patent Agent
312.775.8098
Frank G. Salinas, Ph.D., is a Patent Agent at McAndrews, Held & Malloy. He has significant experience in domestic and foreign patent prosecution, opinions, and litigation. His work has covered a wide range of technologies, including the pharmacological, biotechnical, nutritional, diagnostic, and medical device arts. His prosecution and opinion work focuses on helping clients develop patent portfolios and strategic business initiatives through the comprehensive review and analysis of complex patent and technology landscapes.
Frank received his Ph.D. from the University of Texas, where he was a National Aeronautics and Space Administration (NASA) Fellow in the Department of Chemistry. His research focused on the operation and control of multifunctional enzyme complexes responsible for mediating genetic recombination.
After completing his graduate work, Frank joined Penn State University’s Department of Chemistry as a National Institutes of Health Postdoctoral Fellow. His research at Penn State focused on the development and use of combinatorial protein/peptide libraries and high-throughput screening formats for the directed evolution of novel catalysts and the characterization of bio-effecting synthetic organic compounds. Frank’s research also involved work related to understanding replisome-mediated DNA replication, and the subsequent development of isothermal point-of-care DNA amplification technologies.
Through the years, Frank’s research has been published in journals such as Cell, Nature Biotechnology, Proceedings of the National Academy of Sciences, Journal of the American Chemical Society, Journal of Biological Chemistry, and Annual Review of Biochemistry.
EDUCATION
- Pennsylvania State University, NIH Postdoctoral Fellow
- The University of Texas at Austin, Ph.D. Biochemistry, NASA Graduate Student Fellow
- Saint Mary’s University, B.S. Biology/Chemistry
BAR ADMISSIONS/REGISTRATIONS
- U.S. Patent and Trademark Office
Education
- Pennsylvania State University, NIH Postdoctoral Fellow
- The University of Texas at Austin, Ph.D. Biochemistry, NASA Graduate Student Fellow
- Saint Mary’s University, B.S. Biology/Chemistry
Practices
- Design Rights
- IP Transactions
- IP Litigation
- Post-Grant Practice
- Trademarks & Copyrights
Bar Admissions/Registrations
- U.S. Patent and Trademark Office
Industries
- Chemical
- Computer & Electronics Technology
- Industrial & Mechanical
- Medical Devices
- Life Sciences
- Pharmaceuticals
- Food, Beverage & Nutrition
Honors & Awards
- National Institutes of Health (NIH), National Research Service Award and Postdoctoral Fellowship
- National Aeronautics and Space Administration (NASA), Graduate Student Researchers Program (GSRP) Fellowship
- U.S. Department of Education, Graduate Assistance in Areas of National Need (GAANN) Research Fellowship
- Alberta Heritage Foundation for Medical Research, Heritage Visiting Scientist Research Fellowship
Publications
- Salinas F and Kodadek T, “Strand exchange through a DNA-protein complex requires a DNA helicase,” Biochemical and Biophysical Research Communications, 1994 Dec. 15; 205(2):1004-9
- Salinas F, Jiang H, and Kodadek T, “Homology dependence of UvsX protein-catalyzed joint molecule formation,” Journal of Biological Chemistry, 1995 Mar 10; 270(10):5181 – 5191
- Salinas F and Kodadek T, “Phage T4 homologous strand exchange: a DNA helicase, not the strand transferase, drives polar branch migration,” Cell, 1995 Jul 14;82(1):111-119
- Jiang H, Salinas F, Kodadek T, “The gene 32 single-stranded DNA-binding protein is not bound stably to the phage T4 presynaptic filament,” Biochemical and Biophysical Research Communications, 1997 Feb 24:231(3): 600-5
- Nixon AE, Firestine SM, Salinas F, Benkovic SJ, “Rational design of a scytalone dehydratase-like enzyme using a structurally homologous protein scaffold,” The Proceedings of the National Academy of Sciences U.S.A., 1999 Mar 30;96(7):3568-71
- Firestine SM, Salinas F, Nixon AE, Baker SJ, Benkovic SJ, “Using an AraC-based three-hybrid system to detect biocatalysts in vivo,” Nature Biotechnology, 2000 May;18(5);544-7
- Salinas F and Benkovic SJ “Characterization of bacteriophage T4-coordinated leading- and lagging strand synthesis on a minicircle substrate,” The Proceedings of the National Academy of Sciences U.S.A., 2000 Jun 20:97(13): 7196-7201
- He L, Musik MD, Nicewarner SR, Salinas F, Benkovic SJ, Natan MJ, Keating CD, “Colloidal Au-enhanced Surface Plasma Resonance (SPR) for ultra sensitive detection of DNA hybridization,” The Journal of the American Chemical Society, 2000; 122(38): 9071-9077
- Baker SJ, Firestine SM, Smithrude D, Salinas F, Benkovic SJ, “Synthesis of two bi-functional ligands for the QUEST three-hybrid system,” Tetrahedron Letters, 2000 (41): 7009-7012
- Benkovic SJ, Valentine AM and Salinas F, “Replisome-mediated DNA replication,” Annual Review of Biochemistry, 2001;70:181-208
- Firestine SM, Salinas F, Benkovic SJ, “Using transcriptional-based systems for in vivo enzyme screening,” Methods in Molecular Biology, 2003; 205:315-27
- National Institutes of Health (NIH), National Research Service Award and Postdoctoral Fellowship
- National Aeronautics and Space Administration (NASA), Graduate Student Researchers Program (GSRP) Fellowship
- U.S. Department of Education, Graduate Assistance in Areas of National Need (GAANN) Research Fellowship
- Alberta Heritage Foundation for Medical Research, Heritage Visiting Scientist Research Fellowship
- Salinas F and Kodadek T, “Strand exchange through a DNA-protein complex requires a DNA helicase,” Biochemical and Biophysical Research Communications, 1994 Dec. 15; 205(2):1004-9
- Salinas F, Jiang H, and Kodadek T, “Homology dependence of UvsX protein-catalyzed joint molecule formation,” Journal of Biological Chemistry, 1995 Mar 10; 270(10):5181 – 5191
- Salinas F and Kodadek T, “Phage T4 homologous strand exchange: a DNA helicase, not the strand transferase, drives polar branch migration,” Cell, 1995 Jul 14;82(1):111-119
- Jiang H, Salinas F, Kodadek T, “The gene 32 single-stranded DNA-binding protein is not bound stably to the phage T4 presynaptic filament,” Biochemical and Biophysical Research Communications, 1997 Feb 24:231(3): 600-5
- Nixon AE, Firestine SM, Salinas F, Benkovic SJ, “Rational design of a scytalone dehydratase-like enzyme using a structurally homologous protein scaffold,” The Proceedings of the National Academy of Sciences U.S.A., 1999 Mar 30;96(7):3568-71
- Firestine SM, Salinas F, Nixon AE, Baker SJ, Benkovic SJ, “Using an AraC-based three-hybrid system to detect biocatalysts in vivo,” Nature Biotechnology, 2000 May;18(5);544-7
- Salinas F and Benkovic SJ “Characterization of bacteriophage T4-coordinated leading- and lagging strand synthesis on a minicircle substrate,” The Proceedings of the National Academy of Sciences U.S.A., 2000 Jun 20:97(13): 7196-7201
- He L, Musik MD, Nicewarner SR, Salinas F, Benkovic SJ, Natan MJ, Keating CD, “Colloidal Au-enhanced Surface Plasma Resonance (SPR) for ultra sensitive detection of DNA hybridization,” The Journal of the American Chemical Society, 2000; 122(38): 9071-9077
- Baker SJ, Firestine SM, Smithrude D, Salinas F, Benkovic SJ, “Synthesis of two bi-functional ligands for the QUEST three-hybrid system,” Tetrahedron Letters, 2000 (41): 7009-7012
- Benkovic SJ, Valentine AM and Salinas F, “Replisome-mediated DNA replication,” Annual Review of Biochemistry, 2001;70:181-208
- Firestine SM, Salinas F, Benkovic SJ, “Using transcriptional-based systems for in vivo enzyme screening,” Methods in Molecular Biology, 2003; 205:315-27
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